JPKD (freeware)

(WinXP/NT, Mac OS X or Linux-PC OS) --- Not only include all functionalities of mobilePK, but also has an excellent algorithm of user's defined Bayesian individualized pharmacokinetic parameter estimation (UDBM) for analysis of batch input data. Users can define their own model with population PK parameters using a single-dose, integral equation (for the multiple-dosed) or a steady-state integral equation. The userÕs defined Bayesian model can also be easily applied for the purpose of clinical PK or TDM. More drugs such as carbamazepine, theophylline (IR, SR and IV infusion), lithium, immunosuppressants (tacrolimus and everolimus) and some anti-HIV drugs (indinavir, ritonavir and enfuvirtide) have been added. We also include some model examples for the userÕs defined Bayesian models (such as enoxaparin, imatinib and sirolimus). JPKD runs on any JVM supported desktop platform (WinXP/NT, Mac OS X, Linux-PC or any platform with Java runtime supported). JPKD was created by Jian-ming Lai and Yung-jin Lee. Contact: Yung-jin Lee, Ph.D., e-mail: mobilePK@gmail.com